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Scientific Misconduct: Perceptions, Beliefs, Working Environments, and Reporting Practices in the Clinical Research Associate Population

The purpose of this research study was to survey clinical research associates (CRAs) to obtain information on their attitudes, beliefs, experiences, and reporting practices related to scientific misconduct in clinical trials. This research extended the research conducted by a group of investigators at the University of Alabama (Pryor, E. R., Habermann, B., & Broome, M. E. [in press]. Scientific misconduct from the perspective of research coordinators: A national survey. Journal of Medical Ethics). Data were collected using the Scientific Misconduct Questionnaire-Revised (2), adapted from the questionnaire used by Pryor et al. There were 108 evaluable responders (13.8%) from 783 deliverable surveys sent to CRAs in the Constella Group, LLC, CRA database. Overall, the perceived frequency of misconduct was low except in two areas: protocol violations and adverse event reporting. Observed scientific misconduct by an investigator was reported by 20% of the respondents, and observed misconduct by other research personnel was reported by 17% of the respondents. CRAs with the least experience (0 to 5 years) were more aware of misconduct than more experienced CRAs. CRAs reported misconduct when they observed it, and almost all of them thought their fellow CRAs also would report observed incidents of scientific misconduct. Site environmental influences and individual behavioral influences were perceived to have an impact on scientific misconduct. These findings were exploratory and expanded the body of knowledge on scientific misconduct to the CRA population. However, because of the low response rate, the results are limited in how they can be generalized to the CRA population.

Ethics and Bioethics Webster's Student Dictionary defines ethics as “moral
principles” (Collin, 1999, p. 152). According to Riis (2001), ethics are “the
collection of fundamental values, attitudes, and norms considered by most of the
population ...

Annual Report of the Building Committee of the Cathedral of Saint Peter and Saint Paul

... Catharine M'Callom, Ann M'Attee, Ellen M'Gettigan, Margaret M'Grath, Charles
M'Swiggen, Michael M'Ginnis, James M'Geehan, Patrick M'Govern, James M'
Ginnis, Catharine M'Kane, Philip M'Kellin, Patrick Newland, Professor O'Conner,
 ...

Reports of Cases Argued and Determined in the Supreme Court And, at Law, in the Court of Errors and Appeals of the State of New Jersey

Moersdorf v. N. Y. Telephone Co. 8% N. J. L. killed while in the performance of
his duties in repairing fire department wires, by the falling of a pole erected in a
public highway (Jersey avenue), upon the top bar of which such wires were
strung, ...

Writing Research Reports: A Guide for Graduate Students

Mohammad Ali Salmani Nodoushan. PREFACE. Writing research reports: A
guide for graduate students is designed to foster in undergraduate students the
skills they need for success in their research courses. The book consists of three
 ...

Spiritual intelligence, and the way and means of acquiring it. Report of the Committee on Religious Instruction of the General Convention of the New Church. Reprinted from the New-Jerusalem Magazine, etc

Thus we have, from the doctrine of the church, some definite idea of the way in
which the infant is, by regular steps, to ascend to the exalted intelligence and
peace of a true manhood. We see, also, what may hinder this so desirable result
from ...

Studi kelayakan dan pra rencana terperinci untuk kampung improvement programme kota madya dati II Tanjung Karang, Teluk Betung. Draft final report

Progress Report to the National Advisory Committee for Aeronautics Covering Researc on Heat-Resistant Alloys

The excellent techniques developed by Professor Bigelow are now being
standardized and adopted by metallurgists for more routine studies. Particular
acknowledgments are due to Professor Bigelow for his excellent work in
developing the ...